If heart disease runs in your family, start exercising now

Heart disease: Those 'at genetic risk' less likely to develop illness if they exercise

Nonetheless, the researchers said the data is robust and the results are worthy of consideration in guidelines. "All were associated with lower risk of disease in the future", Dr Ingelsson noted. The scientists compared the data of the women with data on the average female population in the United States and came to the clear conclusion: the risk of dying of heart disease in the long term, after breast cancer treatment is no greater than in the average female population.

The results showed that those who had higher levels of grip strength, physical activity and cardiorespiratory fitness also had a reduced risk of several cardiovascular conditions, including heart attacks, stroke, and atrial fibrillation, even if they had a genetic predisposition for heart disease.

When looking at participants with a high genetic risk, those with a high level of cardiorespiratory fitness had a 49 percent lower risk for coronary heart disease and a 60 percent lower risk for atrial fibrillation compared to those with a low level of fitness.

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"It is particularly good news for the large number of affected patients that if they are in good medical care and have survived breast cancer, they do not need to be more anxious about deadly heart diseases than women at the same age without breast cancer". Researchers followed the participants for about a decade, tracking activity and exercise through questionnaires, grip strength measurements and other tests. "And vice versa: Even if you have a low genetic risk, you should still get exercise".

The study examined 482,702 people in England, Scotland and Wales who participated in a research project known as UK Biobank, which recruited participants between 40 and 69.

For example, people with an intermediate genetic risk for heart disease who were in the group with the strongest grips were 36 percent less likely to develop heart disease and 46 percent less likely to develop atrial fibrillation than participants with the same genetic risk who had the weakest grips.

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One such study reported earlier this year that depression raises the risk of abnormal heart rate by nearly a third, and other research pointed out that having both depression and heart disease can raise the risk of premature death by twofold.

When allowing to the participants to do self-reported exercise, they wore wrist accelerometers, hand dynamometers for grip strength and treadmills for objective measures.

"We can't definitely claim a causal connection, observational studies are created to establish trends".

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"However, some clinical studies have suggested that both chemotherapy and radiotherapy are associated with the risk of suffering from heart disease as a result of treatment", says Hermann Brenner from the German Cancer Research Center. However, for any individual, Dr. Ingelsson advised that "it would be best to discuss a physical activity plan with a physician".

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